======= Inputs ======= The tool requires a path to a ro-crate (directory) passed in ``--inputdir`` parameter as its input. The directory should contain following files: - ``ppi_edgelist.tsv`` A processed edge list file which represents protein-protein interactions, where proteins are identified by their symbols. .. code-block:: geneA geneB DNMT3A SAP18 DNMT3A DDX3X DNMT3A SEC16A DNMT3A U2SURP DNMT3A SYNJ2 - ``ppi_gene_node_attributes.tsv`` Contains attributes for each gene node in the protein-protein interaction network. This includes information like gene names, ensembl ID, and other relevant data. The code directly references only ``name`` column, which is required but also other columns may be present: * name - contains the gene symbol. In some cases, it can contain an ensembl ID or another query, that mygene was queried with. * represents - a comma-separated list of Ensembl gene IDs that the gene symbol represents. * ambiguous - a comma-separated list of gene symbols that are considered ambiguous. * bait - the bait column contains Boolean values (TRUE or FALSE) indicating whether the gene is considered a "bait" in the context of affinity purification mass spectrometry (APMS) experiments. Baits are proteins of interest that are used to pull down interacting partners (preys) from a cell extract. A value of TRUE suggests that the gene is used as a bait in such experiments, as determined by its presence in a provided bait_set. .. code-block:: name represents ambiguous bait DNMT3A ensembl:ENSG00000119772 TRUE HDAC2 ensembl:ENSG00000196591 TRUE KDM6A ensembl:ENSG00000147050 TRUE SMARCA4 ensembl:ENSG00000127616 TRUE - ``ro-crate-metadata.json`` Metadata in RO-Crate format, a community effort to establish a lightweight approach to packaging research data with their metadata. The main object contains identifier (@id), type (@type), name, descriptions, keywords and isPartOf, that describes the hierarchical relationship (organization and project). Graph: The @graph key contains an array of objects that detail other entities related to the main dataset. a. Metadata, Datasets, Software b. Output Files: details of output files generated by the tool.